Berkley Molecular Sciences Institute -- Center for Genomic Experimentation and Computation
We will establish a center that combines functional genomic and computational research to model a prototype signal transduction pathway. Work at the center will focus on the "Alpha Project." The overall goal of the work is to gain the ability to predict the behavior of a well-studied biological regulatory system at the level of individual cells.

Harvard University -- Molecular and Genomic Imaging Center
We propose here the Molecular and Genomic Imaging Center (MGIC) in response to a biomedical-community-wide need for flexible, cost-effective, high-resolution technology to identify and characterize variation in biological systems at the level of genomes and transcriptomes.

Johns Hopkins University -- Center for the Epigenetics of Common Human Disease
Epigenetics is the study of information within the cell that is heritable during cell division, but does not lie within the DNA sequence itself. Epigenetics has been largely ignored in human genomic science, although there is reason to believe that common human diseases may be related to epigenetic modifiers. 

Yale University -- Human Genome Array: Technology for Functional Analysis
We propose to establish a center to build genomic DNA arrays and develop novel technologies that will use these arrays for the large-scale functional analysis of the human genome. 0.3-1.4 kb fragments of nonrepetitive DNA from each of chromosomes 22, 21, 20, 19,7, 17, and perhaps the X chromosome will be prepared by PCR and attached to microscope slides.